Precision peptides,
traceable to the batch.

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic 83-amino acid analogue of human IGF-1, engineered with two structural modifications: substitution of glutamic acid at position 3 with arginine, and addition of a 13-amino acid N-terminal extension (Met-Lys-Arg extension sequence). These modifications dramatically reduce binding affinity for IGF binding proteins (IGFBPs 1–6) compared to native IGF-1, resulting in a prolonged half-life in serum-based assay systems due to reduced sequestration. IGF-1 LR3 signals through the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating downstream PI3K/Akt and Ras/MAPK signaling cascades in cell-based models. It has been widely used as a research reagent in studies of myoblast and satellite cell proliferation, protein synthesis pathway characterization, and insulin receptor substrate (IRS-1/IRS-2) phosphorylation kinetics in skeletal muscle and adipocyte cell culture systems. Researchers also employ IGF-1 LR3 in receptor binding competition assays and IGFBP displacement studies due to its reduced protein-binding profile relative to recombinant human IGF-1. Supplied as a lyophilized powder for in vitro and ex vivo research use only.

All-in-one healing and skin blend (GHK-Cu, KPV, TB-500, BPC-157). 80mg. KLOW is a four-peptide research blend totaling 80mg of lyophilized powder. It contains BPC-157 (10mg), a 15-amino-acid synthetic peptide derived from a sequence found in human gastric juice protein; TB-500 (10mg), a 43-amino-acid fragment of the naturally occurring protein thymosin beta-4; GHK-Cu (50mg), a copper-bound tripeptide first isolated from human blood plasma in 1973; and KPV (10mg), a three-amino-acid fragment from the C-terminal region of alpha-melanocyte-stimulating hormone. The powder appears white to off-white with a faint blue tint from the copper in GHK-Cu. It dissolves readily in water and should be stored refrigerated at 2–8 °C. Each component is a well-characterized peptide with an established chemical identity and published molecular structure. This product is strictly for research purposes only. Not approved for human or animal use.

Copper peptide for skin remodeling, collagen, hair, and wound repair. 100mg. GHK-Cu (glycyl-L-histidyl-L-lysine copper(II) complex) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It has been extensively studied in wound-healing and dermatological research models for its modulation of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) expression in fibroblast cultures. Research has examined its interaction with transforming growth factor-beta (TGF-β) pathways and its effects on collagen and glycosaminoglycan synthesis in extracellular matrix studies. A frequently used reagent in cell migration and tissue remodeling assays. Supplied for in vitro research use only.