Growth Hormone

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic 83-amino acid analogue of human IGF-1, engineered with two structural modifications: substitution of glutamic acid at position 3 with arginine, and addition of a 13-amino acid N-terminal extension (Met-Lys-Arg extension sequence). These modifications dramatically reduce binding affinity for IGF binding proteins (IGFBPs 1–6) compared to native IGF-1, resulting in a prolonged half-life in serum-based assay systems due to reduced sequestration. IGF-1 LR3 signals through the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating downstream PI3K/Akt and Ras/MAPK signaling cascades in cell-based models. It has been widely used as a research reagent in studies of myoblast and satellite cell proliferation, protein synthesis pathway characterization, and insulin receptor substrate (IRS-1/IRS-2) phosphorylation kinetics in skeletal muscle and adipocyte cell culture systems. Researchers also employ IGF-1 LR3 in receptor binding competition assays and IGFBP displacement studies due to its reduced protein-binding profile relative to recombinant human IGF-1. Supplied as a lyophilized powder for in vitro and ex vivo research use only.

GHRH analog proven to strip visceral belly fat and lift IGF-1. 10mg. Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), composed of 44 amino acids with the molecular formula C221H366N72O67S and a molecular weight of 5,135.9 g/mol. It is also known by the research designation TH9507 (CAS 218949-48-5). Its structure is identical to naturally occurring human GHRH, except for a trans-3-hexenoic acid group added to the tyrosine at position 1, which increases its resistance to enzymatic breakdown. Tesamorelin is classified as a GHRH analog and is supplied as a lyophilized white to off-white powder, soluble in water. It requires refrigeration after reconstitution. This product is strictly for research purposes only.

This blend contains CJC-1295 without DAC (5mg) and Ipamorelin (5mg) in a 1:1 ratio, totaling 10mg of lyophilized powder. CJC-1295 without DAC (also called Mod GRF 1-29) is a 29-amino-acid synthetic analog of growth hormone-releasing hormone, engineered with four amino acid substitutions to resist enzymatic degradation. Its molecular weight is approximately 3367 g/mol. Ipamorelin is a pentapeptide — five amino acids — with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂ and a molecular weight of 711.86 g/mol, first described in 1998. The blend is supplied as a white lyophilized powder, water-soluble, and should be stored refrigerated at 2–8 °C.